PDB Information

PDB3TPL
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations
Xu, Y.C., Li, M.J., Greenblatt, H., Chen, W.Y., Paz, A., Dym, O., Peleg, Y., Chen, T.T., Shen, X., He, J.H., Jiang, H.L., Silman, I., Sussman, J.L.
Acta Crystallogr.,Sect.D
HeaderHydrolase
Released2011-09-08
Resolution2.500
CATH Insert Date27 Nov, 2011

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 29 Nov, 2011 Chopped
B 29 Nov, 2011 Chopped
C 29 Nov, 2011 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
3tplA01 01 Dec, 2011 2.40.70.10 Assigned
3tplA02 01 Dec, 2011 2.40.70.10 Assigned
3tplB01 01 Dec, 2011 2.40.70.10 Assigned
3tplB02 01 Dec, 2011 2.40.70.10 Assigned
3tplC01 01 Dec, 2011 2.40.70.10 Assigned
3tplC02 01 Dec, 2011 2.40.70.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1