PDB 3sx4

PDB Links
Overview

PDB Information

PDB	3SX4
Method	X-RAY DIFFRACTION
Host Organism	Pichia pastoris
Gene Source	Homo sapiens
Primary Citation	7-Oxopyrrolopyridine-derived DPP4 inhibitors-mitigation of CYP and hERG liabilities via introduction of polar functionalities in the active site. Wang, W., Devasthale, P., Wang, A., Harrity, T., Egan, D., Morgan, N., Cap, M., Fura, A., Klei, H.E., Kish, K., Weigelt, C., Sun, L., Levesque, P., Li, Y.X., Zahler, R., Kirby, M.S., Hamann, L.G. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2011-07-14
Resolution	2.600
CATH Insert Date	30 Oct, 2011

PDB Images (7)

Image of CATH 3sx4

3sx4

PDB 3sx4

Image of CATH 3sx4A

3sx4A

PDB Chain 3sx4A

Image of CATH 3sx4B

3sx4B

PDB Chain 3sx4B

Image of CATH 3sx4A01

3sx4A01

CATH Domain 3sx4A01

Image of CATH 3sx4A02

3sx4A02

CATH Domain 3sx4A02

Image of CATH 3sx4B01

3sx4B01

CATH Domain 3sx4B01

Image of CATH 3sx4B02

3sx4B02

CATH Domain 3sx4B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	29 Nov, 2011	Chopped
B	29 Nov, 2011	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3sx4A01	01 Dec, 2011	3.40.50.1820	Assigned
3sx4A02	01 Dec, 2011	2.140.10.30	Assigned
3sx4B01	01 Dec, 2011	3.40.50.1820	Assigned
3sx4B02	01 Dec, 2011	2.140.10.30	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P27487	DPP4_HUMAN	Homo sapiens	Dipeptidyl peptidase 4
P27487	DPP4_HUMAN	Homo sapiens	Dipeptidyl peptidase 4