PDB 3sqo

PDB Links
Overview

PDB Information

PDB	3SQO
Method	X-RAY DIFFRACTION
Host Organism	homo sapiens
Gene Source	Homo sapiens
Primary Citation	Proprotein convertase substilisin/kexin type 9 antagonism reduces low-density lipoprotein cholesterol in statin-treated hypercholesterolemic nonhuman primates. Liang, H., Chaparro-Riggers, J., Strop, P., Geng, T., Sutton, J.E., Tsai, D., Bai, L., Abdiche, Y., Dilley, J., Yu, J., Wu, S., Chin, S.M., Lee, N.A., Rossi, A., Lin, J.C., Rajpal, A., Pons, J., Shelton, D.L. J.Pharmacol.Exp.Ther.
Header	Hydrolase/Immune System
Released	2011-07-05
Resolution	2.700
CATH Insert Date	27 May, 2012

PDB Images (12)

Image of CATH 3sqo

3sqo

PDB 3sqo

Image of CATH 3sqoA

3sqoA

PDB Chain 3sqoA

Image of CATH 3sqoH

3sqoH

PDB Chain 3sqoH

Image of CATH 3sqoL

3sqoL

PDB Chain 3sqoL

Image of CATH 3sqoP

3sqoP

PDB Chain 3sqoP

Image of CATH 3sqoA01

3sqoA01

CATH Domain 3sqoA01

Image of CATH 3sqoA02

3sqoA02

CATH Domain 3sqoA02

Image of CATH 3sqoH01

3sqoH01

CATH Domain 3sqoH01

Image of CATH 3sqoH02

3sqoH02

CATH Domain 3sqoH02

Image of CATH 3sqoL01

3sqoL01

CATH Domain 3sqoL01

Image of CATH 3sqoL02

3sqoL02

CATH Domain 3sqoL02

Image of CATH 3sqoP01

3sqoP01

CATH Domain 3sqoP01

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	28 May, 2012	Chopped
H	28 May, 2012	Chopped
L	28 May, 2012	Chopped
P	28 May, 2012	Chopped

CATH Domains (7)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3sqoA01	09 Oct, 2013	3.40.50.200	Assigned
3sqoA02	09 Oct, 2013	2.60.120.690	Assigned
3sqoH01	08 Jun, 2012	2.60.40.10	Assigned
3sqoH02	08 Jun, 2012	2.60.40.10	Assigned
3sqoL01	08 Jun, 2012	2.60.40.10	Assigned
3sqoL02	08 Jun, 2012	2.60.40.10	Assigned
3sqoP01	04 Feb, 2013	3.30.70.80	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q8NBP7	PCSK9_HUMAN	Homo sapiens	Proprotein convertase subtilisin/kexin type 9
Q8NBP7	PCSK9_HUMAN	Homo sapiens	Proprotein convertase subtilisin/kexin type 9