PDB 3skf

PDB Information

PDB3SKF
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Synthesis and in vivo evaluation of cyclic diaminopropane BACE-1 inhibitors.
Thompson, L.A., Shi, J., Decicco, C.P., Tebben, A.J., Olson, R.E., Boy, K.M., Guernon, J.M., Good, A.C., Liauw, A., Zheng, C., Copeland, R.A., Combs, A.P., Trainor, G.L., Camac, D.M., Muckelbauer, J.K., Lentz, K.A., Grace, J.E., Burton, C.R., Toyn, J.H., Barten, D.M., Marcinkeviciene, J., Meredith, J.E., Albright, C.F., Macor, J.E.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2011-06-22
Resolution3.000
CATH Insert Date04 Sep, 2011

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Sep, 2011 Chopped
B 05 Sep, 2011 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3skfA01 07 Sep, 2011 2.40.70.10 Assigned
3skfA02 07 Sep, 2011 2.40.70.10 Assigned
3skfB01 07 Sep, 2011 2.40.70.10 Assigned
3skfB02 07 Sep, 2011 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1