PDB 3sie

PDB Information

PDB3SIE
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Utilization of Halogen Bond in Lead Optimization: A Case Study of Rational Design of Potent Phosphodiesterase Type 5 (PDE5) Inhibitors.
Xu, Z., Liu, Z., Chen, T., Chen, T.T., Wang, Z., Tian, G., Shi, J., Wang, X., Lu, Y., Yan, X., Wang, G., Jiang, H., Chen, K., Wang, S., Xu, Y., Shen, J., Zhu, W.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2011-06-17
Resolution1.930
CATH Insert Date28 Aug, 2011

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Aug, 2011 Chopped
B 29 Aug, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3sieA00 01 Sep, 2011 1.10.1300.10 Assigned
3sieB00 01 Sep, 2011 1.10.1300.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O76074 PDE5A_HUMAN Homo sapiens cGMP-specific 3',5'-cyclic phosphodiesterase
O76074 PDE5A_HUMAN Homo sapiens cGMP-specific 3',5'-cyclic phosphodiesterase