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PDB Information
| PDB | 3S7A |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation |
Structural analysis of human dihydrofolate reductase as a binary complex with the potent and selective inhibitor 2,4-diamino-6-{2'-O-(3-carboxypropyl)oxydibenz[b,f]-azepin-5-yl}methylpteridine reveals an unusual binding mode.
Cody, V., Pace, J., Nowak, J.
Acta Crystallogr.,Sect.D
|
| Header | Oxidoreductase/Oxidoreductase Inhibitor |
| Released | 2011-05-26 |
| Resolution | 1.800 |
| CATH Insert Date | 09 Oct, 2011 |
PDB Images (3)
3s7aA00
CATH Domain 3s7aA00
PDB Chains (1)
| Chain ID | Date inserted into CATH | CATH Status |
| A | 29 Nov, 2011 | Chopped
|
CATH Domains (1)
UniProtKB Entries (1)
| Accession |
Gene ID |
Taxon |
Description |
| P00374 |
DYR_HUMAN |
Homo sapiens |
Dihydrofolate reductase |