PDB 3r4b

PDB Information

PDB3R4B
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus 1
Primary Citation
TMC310911, a Novel Human Immunodeficiency Virus Type 1 Protease Inhibitor, Shows In Vitro an Improved Resistance Profile and Higher Genetic Barrier to Resistance Compared with Current Protease Inhibitors.
Dierynck, I., Van Marck, H., Van Ginderen, M., Jonckers, T.H., Nalam, M.N., Schiffer, C.A., Raoof, A., Kraus, G., Picchio, G.
Antimicrob.Agents Chemother.
HeaderHydrolase/Hydrolase Inhibitor
Released2011-03-17
Resolution1.900
CATH Insert Date26 Sep, 2011

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Nov, 2011 Chopped
B 29 Nov, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3r4bA00 01 Dec, 2011 2.40.70.10 Assigned
3r4bB00 01 Dec, 2011 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03369 POL_HV1A2 HIV-1 M:B_ARV2/SF2 Gag-Pol polyprotein
P03369 POL_HV1A2 HIV-1 M:B_ARV2/SF2 Gag-Pol polyprotein