PDB Information

PDB3R49
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities.
Ahmed-Belkacem, A., Colliandre, L., Ahnou, N., Nevers, Q., Gelin, M., Bessin, Y., Brillet, R., Cala, O., Douguet, D., Bourguet, W., Krimm, I., Pawlotsky, J.M., Guichou, J.F.
Nat Commun
HeaderIsomerase/Isomerase Inhibitor
Released2011-03-17
Resolution1.770
CATH Insert Date27 May, 2012

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3r49A00 05 Feb, 2013 2.40.100.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P30405 PPIF_HUMAN Homo sapiens Peptidyl-prolyl cis-trans isomerase F, mitochondrial