PDB 3qqu

PDB Information

PDB3QQU
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of 2,4-bis-arylamino-1,3-pyrimidines as insulin-like growth factor-1 receptor (IGF-1R) inhibitors.
Buchanan, J.L., Newcomb, J.R., Carney, D.P., Chaffee, S.C., Chai, L., Cupples, R., Epstein, L.F., Gallant, P., Gu, Y., Harmange, J.C., Hodge, K., Houk, B.E., Huang, X., Jona, J., Joseph, S., Jun, H.T., Kumar, R., Li, C., Lu, J., Menges, T., Morrison, M.J., Novak, P.M., van der Plas, S., Radinsky, R., Rose, P.E., Sawant, S., Sun, J.R., Surapaneni, S., Turci, S.M., Xu, K., Yanez, E., Zhao, H., Zhu, X.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2011-02-16
Resolution2.900
CATH Insert Date24 Apr, 2011

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 25 Apr, 2011 Chopped
B 25 Apr, 2011 Chopped
C 25 Apr, 2011 Chopped
D 25 Apr, 2011 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3qquA01 04 May, 2011 3.30.200.20 Assigned
3qquA02 04 May, 2011 1.10.510.10 Assigned
3qquB01 03 May, 2011 3.30.200.20 Assigned
3qquB02 03 May, 2011 1.10.510.10 Assigned
3qquC01 04 May, 2011 3.30.200.20 Assigned
3qquC02 04 May, 2011 1.10.510.10 Assigned
3qquD01 04 May, 2011 3.30.200.20 Assigned
3qquD02 04 May, 2011 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P08069 IGF1R_HUMAN Homo sapiens Insulin-like growth factor 1 receptor
P08069 IGF1R_HUMAN Homo sapiens Insulin-like growth factor 1 receptor
P08069 IGF1R_HUMAN Homo sapiens Insulin-like growth factor 1 receptor
P08069 IGF1R_HUMAN Homo sapiens Insulin-like growth factor 1 receptor