PDB Information

PDB3QCG
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop
Sheriff, S., Beno, B.R., Zhai, W., Kostich, W.A., McDonnell, P.A., Kish, K., Goldfarb, V., Gao, M., Kiefer, S.E., Yanchunas, J., Huang, Y., Shi, S., Zhu, S., Dzierba, C., Bronson, J., Macor, J.E., Appiah, K.K., Westphal, R.S., O'Connell, J., Gerritz, S.W.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2011-01-16
Resolution2.050
CATH Insert Date08 Jan, 2012

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 09 Jan, 2012 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3qcgA00 16 Jan, 2012 3.90.190.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P23470 PTPRG_HUMAN Homo sapiens Receptor-type tyrosine-protein phosphatase gamma