PDB Information

PDB3P70
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structural basis of thrombin-mediated factor V activation: the Glu666-Glu672 sequence is critical for processing at the heavy chain-B domain junction.
Corral-Rodriguez, M.A., Bock, P.E., Hernandez-Carvajal, E., Gutierrez-Gallego, R., Fuentes-Prior, P.
Blood
HeaderHydrolase
Released2010-10-11
Resolution2.550
CATH Insert Date02 Oct, 2011

PDB Images (21)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 29 Nov, 2011 Rejected
B 29 Nov, 2011 Chopped
C 29 Nov, 2011 Rejected
D 29 Nov, 2011 Chopped
E 29 Nov, 2011 Rejected
F 29 Nov, 2011 Chopped
G 29 Nov, 2011 Rejected
H 29 Nov, 2011 Chopped
M 29 Nov, 2011 Rejected
N 29 Nov, 2011 Rejected
O 29 Nov, 2011 Rejected
P 29 Nov, 2011 Rejected

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3p70B01 01 Dec, 2011 2.40.10.10 Assigned
3p70B02 01 Dec, 2011 2.40.10.10 Assigned
3p70D01 01 Dec, 2011 2.40.10.10 Assigned
3p70D02 01 Dec, 2011 2.40.10.10 Assigned
3p70F01 01 Dec, 2011 2.40.10.10 Assigned
3p70F02 01 Dec, 2011 2.40.10.10 Assigned
3p70H01 01 Dec, 2011 2.40.10.10 Assigned
3p70H02 01 Dec, 2011 2.40.10.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
P12259 FA5_HUMAN Homo sapiens Coagulation factor V
P12259 FA5_HUMAN Homo sapiens Coagulation factor V
P00734 THRB_HUMAN Homo sapiens Prothrombin
P00734 THRB_HUMAN Homo sapiens Prothrombin
P12259 FA5_HUMAN Homo sapiens Coagulation factor V
P00734 THRB_HUMAN Homo sapiens Prothrombin
P00734 THRB_HUMAN Homo sapiens Prothrombin
P12259 FA5_HUMAN Homo sapiens Coagulation factor V
P00734 THRB_HUMAN Homo sapiens Prothrombin
P00734 THRB_HUMAN Homo sapiens Prothrombin
P00734 THRB_HUMAN Homo sapiens Prothrombin
P00734 THRB_HUMAN Homo sapiens Prothrombin