PDB 3orn

PDB Information

PDB3ORN
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design and synthesis of novel allosteric MEK inhibitor CH4987655 as an orally available anticancer agent.
Isshiki, Y., Kohchi, Y., Iikura, H., Matsubara, Y., Asoh, K., Murata, T., Kohchi, M., Mizuguchi, E., Tsujii, S., Hattori, K., Miura, T., Yoshimura, Y., Aida, S., Miwa, M., Saitoh, R., Murao, N., Okabe, H., Belunis, C., Janson, C., Lukacs, C., Schuck, V., Shimma, N.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2010-09-07
Resolution2.800
CATH Insert Date06 Mar, 2011

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 06 Mar, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3ornA01 25 Sep, 2013 3.30.200.20 Assigned
3ornA02 25 Sep, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q02750 MP2K1_HUMAN Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1