PDB 3nbp

PDB Information

PDB3NBP
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus type 1 group M subtype B
Primary Citation
Discovery of piperidin-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-benzyl derivatives with broad potency against resistant mutant viruses.
Kertesz, D.J., Brotherton-Pleiss, C., Yang, M., Wang, Z., Lin, X., Qiu, Z., Hirschfeld, D.R., Gleason, S., Mirzadegan, T., Dunten, P.W., Harris, S.F., Villasenor, A.G., Hang, J.Q., Heilek, G.M., Klumpp, K.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2010-06-03
Resolution2.950
CATH Insert Date22 Aug, 2010

PDB Images (12)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 23 Aug, 2010 Chopped
B 23 Aug, 2010 Chopped

CATH Domains (9)

Domain ID Date inserted into CATH Superfamily CATH Status
3nbpA01 19 Oct, 2010 3.10.10.10 Assigned
3nbpA02 19 Oct, 2010 3.30.70.270 Assigned
3nbpA03 19 Oct, 2010 3.30.70.270 Assigned
3nbpA04 19 Oct, 2010 3.30.70.270 Assigned
3nbpA05 19 Oct, 2010 3.30.420.10 Assigned
3nbpB01 20 Oct, 2010 3.10.10.10 Assigned
3nbpB02 20 Oct, 2010 3.30.70.270 Assigned
3nbpB03 20 Oct, 2010 3.30.70.270 Assigned
3nbpB04 20 Oct, 2010 3.30.70.270 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P04585 POL_HV1H2 HIV-1 M:B_HXB2R Gag-Pol polyprotein
P04585 POL_HV1H2 HIV-1 M:B_HXB2R Gag-Pol polyprotein