PDB Information

PDB3N3G
MethodX-RAY DIFFRACTION
Host OrganismTrichoplusia ni
Gene SourceHomo sapiens
Primary Citation
4-(3-Trifluoromethylphenyl)-pyrimidine-2-carbonitrile as cathepsin S inhibitors: N3, not N1 is critically important.
Cai, J., Fradera, X., van Zeeland, M., Dempster, M., Cameron, K.S., Bennett, D.J., Robinson, J., Popplestone, L., Baugh, M., Westwood, P., Bruin, J., Hamilton, W., Kinghorn, E., Long, C., Uitdehaag, J.C.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2010-05-20
Resolution1.600
CATH Insert Date15 Aug, 2010

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2010 Chopped
B 16 Aug, 2010 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3n3gA00 16 Oct, 2010 3.90.70.10 Assigned
3n3gB00 16 Oct, 2010 3.90.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P25774 CATS_HUMAN Homo sapiens Cathepsin S
P25774 CATS_HUMAN Homo sapiens Cathepsin S