PDB 3mg0

PDB Links
Overview

PDB Information

PDB	3MG0
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S beta5-subunit. Blackburn, C., Gigstad, K.M., Hales, P., Garcia, K., Jones, M., Bruzzese, F.J., Barrett, C., Liu, J.X., Soucy, T.A., Sappal, D.S., Bump, N., Olhava, E.J., Fleming, P., Dick, L.R., Tsu, C., Sintchak, M.D., Blank, J.L. Biochem.J.
Header	Hydrolase
Released	2010-04-05
Resolution	2.680
CATH Insert Date	22 May, 2011

PDB Images (57)

3mg0

PDB 3mg0

3mg01

PDB Chain 3mg01

3mg02

PDB Chain 3mg02

3mg0A

PDB Chain 3mg0A

3mg0B

PDB Chain 3mg0B

3mg0C

PDB Chain 3mg0C

3mg0D

PDB Chain 3mg0D

3mg0E

PDB Chain 3mg0E

3mg0F

PDB Chain 3mg0F

3mg0G

PDB Chain 3mg0G

3mg0H

PDB Chain 3mg0H

3mg0I

PDB Chain 3mg0I

3mg0J

PDB Chain 3mg0J

3mg0K

PDB Chain 3mg0K

3mg0L

PDB Chain 3mg0L

3mg0M

PDB Chain 3mg0M

3mg0N

PDB Chain 3mg0N

3mg0O

PDB Chain 3mg0O

3mg0P

PDB Chain 3mg0P

3mg0Q

PDB Chain 3mg0Q

3mg0R

PDB Chain 3mg0R

3mg0S

PDB Chain 3mg0S

3mg0T

PDB Chain 3mg0T

3mg0U

PDB Chain 3mg0U

3mg0V

PDB Chain 3mg0V

3mg0W

PDB Chain 3mg0W

3mg0X

PDB Chain 3mg0X

3mg0Y

PDB Chain 3mg0Y

3mg0Z

PDB Chain 3mg0Z

3mg0100

CATH Domain 3mg0100

3mg0200

CATH Domain 3mg0200

3mg0A00

CATH Domain 3mg0A00

3mg0B00

CATH Domain 3mg0B00

3mg0C00

CATH Domain 3mg0C00

3mg0D00

CATH Domain 3mg0D00

3mg0E00

CATH Domain 3mg0E00

3mg0F00

CATH Domain 3mg0F00

3mg0G00

CATH Domain 3mg0G00

3mg0H00

CATH Domain 3mg0H00

3mg0I00

CATH Domain 3mg0I00

3mg0J00

CATH Domain 3mg0J00

3mg0K00

CATH Domain 3mg0K00

3mg0L00

CATH Domain 3mg0L00

3mg0M00

CATH Domain 3mg0M00

3mg0N00

CATH Domain 3mg0N00

3mg0O00

CATH Domain 3mg0O00

3mg0P00

CATH Domain 3mg0P00

3mg0Q00

CATH Domain 3mg0Q00

3mg0R00

CATH Domain 3mg0R00

3mg0S00

CATH Domain 3mg0S00

3mg0T00

CATH Domain 3mg0T00

3mg0U00

CATH Domain 3mg0U00

3mg0V00

CATH Domain 3mg0V00

3mg0W00

CATH Domain 3mg0W00

3mg0X00

CATH Domain 3mg0X00

3mg0Y00

CATH Domain 3mg0Y00

3mg0Z00

CATH Domain 3mg0Z00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
1	23 May, 2011	Chopped
2	23 May, 2011	Chopped
A	23 May, 2011	Chopped
B	23 May, 2011	Chopped
C	23 May, 2011	Chopped
D	23 May, 2011	Chopped
E	23 May, 2011	Chopped
F	23 May, 2011	Chopped
G	23 May, 2011	Chopped
H	23 May, 2011	Chopped
I	23 May, 2011	Chopped
J	23 May, 2011	Chopped
K	23 May, 2011	Chopped
L	23 May, 2011	Chopped
M	23 May, 2011	Chopped
N	23 May, 2011	Chopped
O	23 May, 2011	Chopped
P	23 May, 2011	Chopped
Q	23 May, 2011	Chopped
R	23 May, 2011	Chopped
S	23 May, 2011	Chopped
T	23 May, 2011	Chopped
U	23 May, 2011	Chopped
V	23 May, 2011	Chopped
W	23 May, 2011	Chopped
X	23 May, 2011	Chopped
Y	23 May, 2011	Chopped
Z	23 May, 2011	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3mg0100	27 May, 2011	3.60.20.10	Assigned
3mg0200	27 May, 2011	3.60.20.10	Assigned
3mg0A00	04 Feb, 2013	3.60.20.10	Assigned
3mg0B00	04 Feb, 2013	3.60.20.10	Assigned
3mg0C00	04 Feb, 2013	3.60.20.10	Assigned
3mg0D00	08 Feb, 2013	3.60.20.10	Assigned
3mg0E00	27 May, 2011	3.60.20.10	Assigned
3mg0F00	27 May, 2011	3.60.20.10	Assigned
3mg0G00	26 May, 2011	3.60.20.10	Assigned
3mg0H00	27 May, 2011	3.60.20.10	Assigned
3mg0I00	27 May, 2011	3.60.20.10	Assigned
3mg0J00	26 May, 2011	3.60.20.10	Assigned
3mg0K00	26 May, 2011	3.60.20.10	Assigned
3mg0L00	26 May, 2011	3.60.20.10	Assigned
3mg0M00	27 May, 2011	3.60.20.10	Assigned
3mg0N00	26 May, 2011	3.60.20.10	Assigned
3mg0O00	04 Feb, 2013	3.60.20.10	Assigned
3mg0P00	04 Feb, 2013	3.60.20.10	Assigned
3mg0Q00	04 Feb, 2013	3.60.20.10	Assigned
3mg0R00	08 Feb, 2013	3.60.20.10	Assigned
3mg0S00	27 May, 2011	3.60.20.10	Assigned
3mg0T00	27 May, 2011	3.60.20.10	Assigned
3mg0U00	27 May, 2011	3.60.20.10	Assigned
3mg0V00	26 May, 2011	3.60.20.10	Assigned
3mg0W00	26 May, 2011	3.60.20.10	Assigned
3mg0X00	26 May, 2011	3.60.20.10	Assigned
3mg0Y00	26 May, 2011	3.60.20.10	Assigned
3mg0Z00	26 May, 2011	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6