PDB 3m8q

PDB Information

PDB3M8Q
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus type 1
Primary Citation
Discovery of piperidin-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-benzyl derivatives with broad potency against resistant mutant viruses.
Kertesz, D.J., Brotherton-Pleiss, C., Yang, M., Wang, Z., Lin, X., Qiu, Z., Hirschfeld, D.R., Gleason, S., Mirzadegan, T., Dunten, P.W., Harris, S.F., Villasenor, A.G., Hang, J.Q., Heilek, G.M., Klumpp, K.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2010-03-18
Resolution2.700
CATH Insert Date23 May, 2010

PDB Images (12)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 24 May, 2010 Chopped
B 24 May, 2010 Chopped

CATH Domains (9)

Domain ID Date inserted into CATH Superfamily CATH Status
3m8qA01 28 Jul, 2010 3.10.10.10 Assigned
3m8qA02 28 Jul, 2010 3.30.70.270 Assigned
3m8qA03 28 Jul, 2010 3.30.70.270 Assigned
3m8qA04 28 Jul, 2010 3.30.70.270 Assigned
3m8qA05 28 Jul, 2010 3.30.420.10 Assigned
3m8qB01 28 Jul, 2010 3.10.10.10 Assigned
3m8qB02 28 Jul, 2010 3.30.70.270 Assigned
3m8qB03 28 Jul, 2010 3.30.70.270 Assigned
3m8qB04 28 Jul, 2010 3.30.70.270 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P04585 POL_HV1H2 HIV-1 M:B_HXB2R Gag-Pol polyprotein
P04585 POL_HV1H2 HIV-1 M:B_HXB2R Gag-Pol polyprotein