PDB 3m8p

PDB Information

PDB3M8P
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus type 1
Primary Citation
Discovery of piperidin-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-benzyl derivatives with broad potency against resistant mutant viruses.
Kertesz, D.J., Brotherton-Pleiss, C., Yang, M., Wang, Z., Lin, X., Qiu, Z., Hirschfeld, D.R., Gleason, S., Mirzadegan, T., Dunten, P.W., Harris, S.F., Villasenor, A.G., Hang, J.Q., Heilek, G.M., Klumpp, K.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2010-03-18
Resolution2.670
CATH Insert Date23 May, 2010

PDB Images (12)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 24 May, 2010 Chopped
B 24 May, 2010 Chopped

CATH Domains (9)

Domain ID Date inserted into CATH Superfamily CATH Status
3m8pA01 28 Jul, 2010 3.10.10.10 Assigned
3m8pA02 28 Jul, 2010 3.30.70.270 Assigned
3m8pA03 28 Jul, 2010 3.30.70.270 Assigned
3m8pA04 28 Jul, 2010 3.30.70.270 Assigned
3m8pA05 28 Jul, 2010 3.30.420.10 Assigned
3m8pB01 28 Jul, 2010 3.10.10.10 Assigned
3m8pB02 28 Jul, 2010 3.30.70.270 Assigned
3m8pB03 28 Jul, 2010 3.30.70.270 Assigned
3m8pB04 28 Jul, 2010 3.30.70.270 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P04585 POL_HV1H2 HIV-1 M:B_HXB2R Gag-Pol polyprotein
P04585 POL_HV1H2 HIV-1 M:B_HXB2R Gag-Pol polyprotein