PDB 3lj3

PDB Links
Overview

PDB Information

PDB	3LJ3
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery and optimization of 2-(4-substituted-pyrrolo[2,3-b]pyridin-3-yl)methylene-4-hydroxybenzofuran-3(2H)-ones as potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR). Tsou, H.R., MacEwan, G., Birnberg, G., Grosu, G., Bursavich, M.G., Bard, J., Brooijmans, N., Toral-Barza, L., Hollander, I., Mansour, T.S., Ayral-Kaloustian, S., Yu, K. Bioorg.Med.Chem.Lett.
Header	Transferase
Released	2010-01-25
Resolution	2.430
CATH Insert Date	18 Apr, 2010

PDB Images (7)

Image of CATH 3lj3

3lj3

PDB 3lj3

Image of CATH 3lj3A

3lj3A

PDB Chain 3lj3A

Image of CATH 3lj3A01

3lj3A01

CATH Domain 3lj3A01

Image of CATH 3lj3A02

3lj3A02

CATH Domain 3lj3A02

Image of CATH 3lj3A03

3lj3A03

CATH Domain 3lj3A03

Image of CATH 3lj3A04

3lj3A04

CATH Domain 3lj3A04

Image of CATH 3lj3A05

3lj3A05

CATH Domain 3lj3A05

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	18 Apr, 2010	Chopped

CATH Domains (5)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3lj3A01	09 Jul, 2010	3.10.20.90	Assigned
3lj3A02	09 Jul, 2010	2.60.40.150	Assigned
3lj3A03	09 Jul, 2010	1.25.40.70	Assigned
3lj3A04	09 Jul, 2010	3.30.1010.10	Assigned
3lj3A05	09 Jul, 2010	1.10.1070.11	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P48736	PK3CG_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform