PDB 3l3l

PDB Information

PDB3L3L
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and SAR of substituted 3-oxoisoindoline-4-carboxamides as potent inhibitors of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer.
Gandhi, V.B., Luo, Y., Liu, X., Shi, Y., Klinghofer, V., Johnson, E.F., Park, C., Giranda, V.L., Penning, T.D., Zhu, G.D.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2009-12-17
Resolution2.500
CATH Insert Date23 Jan, 2011

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 24 Jan, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3l3lA01 16 Feb, 2011 1.20.142.10 Assigned
3l3lA02 16 Feb, 2011 3.90.228.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1