PDB 3irm

PDB Information

PDB3IRM
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceTrypanosoma cruzi
Primary Citation
Structural basis of antifolate inhibition of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase
Chitnumsub, P., Yuvaniyama, J., Vilaivan, T., Vanichtanankul, J., Kamchonwongpaisan, S., Yuthavong, Y.
To be Published
HeaderOxidoreductase, Transferase
Released2009-08-24
Resolution2.100
CATH Insert Date15 Aug, 2010

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2010 Chopped
B 16 Aug, 2010 Chopped
C 16 Aug, 2010 Chopped
D 16 Aug, 2010 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3irmA01 11 May, 2013 3.40.430.10 Assigned
3irmA02 11 May, 2013 3.30.572.10 Assigned
3irmB01 11 May, 2013 3.40.430.10 Assigned
3irmB02 11 May, 2013 3.30.572.10 Assigned
3irmC01 11 May, 2013 3.40.430.10 Assigned
3irmC02 11 May, 2013 3.30.572.10 Assigned
3irmD01 11 May, 2013 3.40.430.10 Assigned
3irmD02 11 May, 2013 3.30.572.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q27793 DRTS_TRYCR Trypanosoma cruzi Bifunctional dihydrofolate reductase-thymidylate synthase
Q27793 DRTS_TRYCR Trypanosoma cruzi Bifunctional dihydrofolate reductase-thymidylate synthase
Q27793 DRTS_TRYCR Trypanosoma cruzi Bifunctional dihydrofolate reductase-thymidylate synthase
Q27793 DRTS_TRYCR Trypanosoma cruzi Bifunctional dihydrofolate reductase-thymidylate synthase