PDB Information

PDB3IQV
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.
Molzan, M., Schumacher, B., Ottmann, C., Baljuls, A., Polzien, L., Weyand, M., Thiel, P., Rose, R., Rose, M., Kuhenne, P., Kaiser, M., Rapp, U.R., Kuhlmann, J., Ottmann, C.
Mol.Cell.Biol.
HeaderProtein Binding, Signaling Protein
Released2009-08-21
Resolution1.200
CATH Insert Date05 Sep, 2010

PDB Images (4)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 06 Sep, 2010 Chopped
P 06 Sep, 2010 Rejected

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3iqvA00 19 Sep, 2010 1.20.190.20 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P04049 RAF1_HUMAN Homo sapiens RAF proto-oncogene serine/threonine-protein kinase
P31947 1433S_HUMAN Homo sapiens 14-3-3 protein sigma