PDB 3igv

PDB Information

PDB3IGV
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus (isolate BK)
Primary Citation
5,5'- and 6,6'-dialkyl-5,6-dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase.
Ellis, D.A., Blazel, J.K., Tran, C.V., Ruebsam, F., Murphy, D.E., Li, L.S., Zhao, J., Zhou, Y., McGuire, H.M., Xiang, A.X., Webber, S.E., Zhao, Q., Han, Q., Kissinger, C.R., Lardy, M., Gobbi, A., Showalter, R.E., Shah, A.M., Tsan, M., Patel, R.A., LeBrun, L.A., Kamran, R., Bartkowski, D.M., Nolan, T.G., Norris, D.A., Sergeeva, M.V., Kirkovsky, L.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2009-07-28
Resolution2.600
CATH Insert Date10 Dec, 2009

PDB Images (11)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 10 Dec, 2009 Chopped
B 10 Dec, 2009 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3igvA01 03 Oct, 2013 Holding pen
3igvA02 03 Oct, 2013 Holding pen
3igvA03 03 Oct, 2013 3.30.70.270 Assigned
3igvA04 03 Oct, 2013 Holding pen
3igvB01 03 Oct, 2013 Holding pen
3igvB02 03 Oct, 2013 Holding pen
3igvB03 03 Oct, 2013 3.30.70.270 Assigned
3igvB04 03 Oct, 2013 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P26663 POLG_HCVBK Hepatitis C virus (isolate BK) Genome polyprotein
P26663 POLG_HCVBK Hepatitis C virus (isolate BK) Genome polyprotein