PDB Information

PDB3I7G
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Improving potency and selectivity of a new class of non-Zn-chelating MMP-13 inhibitors.
Heim-Riether, A., Taylor, S.J., Liang, S., Gao, D.A., Xiong, Z., Michael August, E., Collins, B.K., Farmer, B.T., Haverty, K., Hill-Drzewi, M., Junker, H.D., Mariana Margarit, S., Moss, N., Neumann, T., Proudfoot, J.R., Keenan, L.S., Sekul, R., Zhang, Q., Li, J., Farrow, N.A.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2009-07-08
Resolution1.950
CATH Insert Date03 Sep, 2009

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Sep, 2009 Chopped
B 03 Sep, 2009 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3i7gA00 18 Mar, 2011 3.40.390.10 Assigned
3i7gB00 18 Mar, 2011 3.40.390.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P45452 MMP13_HUMAN Homo sapiens Collagenase 3
P45452 MMP13_HUMAN Homo sapiens Collagenase 3