PDB Information

PDB3HVG
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Fragment-Based Discovery of BACE1 Inhibitors Using Functional Assays
Godemann, R., Madden, J., Kramer, J., Smith, M.A., Fritz, U., Hesterkamp, T., Barker, J., Hoeppner, S., Hallett, D., Cesura, A., Ebneth, A., Kemp, J.
Biochemistry
HeaderHydrolase
Released2009-06-16
Resolution2.260
CATH Insert Date15 Nov, 2009

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 15 Nov, 2009 Chopped
B 15 Nov, 2009 Chopped
C 15 Nov, 2009 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
3hvgA01 06 Mar, 2010 2.40.70.10 Assigned
3hvgA02 06 Mar, 2010 2.40.70.10 Assigned
3hvgB01 06 Mar, 2010 2.40.70.10 Assigned
3hvgB02 06 Mar, 2010 2.40.70.10 Assigned
3hvgC01 06 Mar, 2010 2.40.70.10 Assigned
3hvgC02 06 Mar, 2010 2.40.70.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1