PDB 3gyn

PDB Information

PDB3GYN
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus (isolate BK)
Primary Citation
5,5'- and 6,6'-dialkyl-5,6-dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase.
Ellis, D.A., Blazel, J.K., Tran, C.V., Ruebsam, F., Murphy, D.E., Li, L.S., Zhao, J., Zhou, Y., McGuire, H.M., Xiang, A.X., Webber, S.E., Zhao, Q., Han, Q., Kissinger, C.R., Lardy, M., Gobbi, A., Showalter, R.E., Shah, A.M., Tsan, M., Patel, R.A., LeBrun, L.A., Kamran, R., Bartkowski, D.M., Nolan, T.G., Norris, D.A., Sergeeva, M.V., Kirkovsky, L.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2009-04-04
Resolution2.150
CATH Insert Date10 Dec, 2009

PDB Images (11)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 10 Dec, 2009 Chopped
B 10 Dec, 2009 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3gynA01 03 Oct, 2013 Holding pen
3gynA02 03 Oct, 2013 Holding pen
3gynA03 03 Oct, 2013 3.30.70.270 Assigned
3gynA04 03 Oct, 2013 Holding pen
3gynB01 03 Oct, 2013 Holding pen
3gynB02 03 Oct, 2013 Holding pen
3gynB03 03 Oct, 2013 3.30.70.270 Assigned
3gynB04 03 Oct, 2013 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P26663 POLG_HCVBK Hepatitis C virus (isolate BK) Genome polyprotein
P26663 POLG_HCVBK Hepatitis C virus (isolate BK) Genome polyprotein