PDB 3gn2

PDB Links
Overview

PDB Information

PDB	3GN2
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	Trypanosoma brucei brucei
Primary Citation	One scaffold, three binding modes: novel and selective pteridine reductase 1 inhibitors derived from fragment hits discovered by virtual screening. Mpamhanga, C.P., Spinks, D., Tulloch, L.B., Shanks, E.J., Robinson, D.A., Collie, I.T., Fairlamb, A.H., Wyatt, P.G., Frearson, J.A., Hunter, W.N., Gilbert, I.H., Brenk, R. J.Med.Chem.
Header	Oxidoreductase
Released	2009-03-16
Resolution	1.600
CATH Insert Date	31 Dec, 2009

PDB Images (9)

Image of CATH 3gn2

3gn2

PDB 3gn2

Image of CATH 3gn2A

3gn2A

PDB Chain 3gn2A

Image of CATH 3gn2B

3gn2B

PDB Chain 3gn2B

Image of CATH 3gn2C

3gn2C

PDB Chain 3gn2C

Image of CATH 3gn2D

3gn2D

PDB Chain 3gn2D

Image of CATH 3gn2A00

3gn2A00

CATH Domain 3gn2A00

Image of CATH 3gn2B00

3gn2B00

CATH Domain 3gn2B00

Image of CATH 3gn2C00

3gn2C00

CATH Domain 3gn2C00

Image of CATH 3gn2D00

3gn2D00

CATH Domain 3gn2D00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	31 Dec, 2009	Chopped
B	31 Dec, 2009	Chopped
C	31 Dec, 2009	Chopped
D	31 Dec, 2009	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3gn2A00	09 Jan, 2010	3.40.50.720	Assigned
3gn2B00	09 Jan, 2010	3.40.50.720	Assigned
3gn2C00	09 Jan, 2010	3.40.50.720	Assigned
3gn2D00	09 Jan, 2010	3.40.50.720	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
O76290	O76290_TRYBB	Trypanosoma brucei brucei	Pteridine reductase
O76290	O76290_TRYBB	Trypanosoma brucei brucei	Pteridine reductase
O76290	O76290_TRYBB	Trypanosoma brucei brucei	Pteridine reductase
O76290	O76290_TRYBB	Trypanosoma brucei brucei	Pteridine reductase