PDB 3gga

PDB Information

PDB3GGA
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus 1
Primary Citation
2-Pyridyl P1'-substituted symmetry-based human immunodeficiency virus protease inhibitors (A-792611 and A-790742) with potential for convenient dosing and reduced side effects.
Degoey, D.A., Grampovnik, D.J., Flentge, C.A., Flosi, W.J., Chen, H.J., Yeung, C.M., Randolph, J.T., Klein, L.L., Dekhtyar, T., Colletti, L., Marsh, K.C., Stoll, V., Mamo, M., Morfitt, D.C., Nguyen, B., Schmidt, J.M., Swanson, S.J., Mo, H., Kati, W.M., Molla, A., Kempf, D.J.
J.Med.Chem.
HeaderHydrolase
Released2009-02-27
Resolution2.500
CATH Insert Date16 Aug, 2009

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped
B 16 Aug, 2009 Chopped
C 16 Aug, 2009 Chopped
D 16 Aug, 2009 Chopped
G 16 Aug, 2009 Chopped
H 16 Aug, 2009 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
3ggaA00 25 Dec, 2009 2.40.70.10 Assigned
3ggaB00 25 Dec, 2009 2.40.70.10 Assigned
3ggaC00 26 Dec, 2009 2.40.70.10 Assigned
3ggaD00 25 Dec, 2009 2.40.70.10 Assigned
3ggaG00 25 Dec, 2009 2.40.70.10 Assigned
3ggaH00 25 Dec, 2009 2.40.70.10 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
CATH-Gene3D is a Global Biodata Core Resource Learn more...