PDB Information

PDB3FRD
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceStaphylococcus aureus
Primary Citation
Increased hydrophobic interactions of iclaprim with Staphylococcus aureus dihydrofolate reductase are responsible for the increase in affinity and antibacterial activity
Oefner, C., Bandera, M., Haldimann, A., Laue, H., Schulz, H., Mukhija, S., Parisi, S., Weiss, L., Lociuro, S., Dale, G.E.
J.Antimicrob.Chemother.
HeaderOxidoreductase
Released2009-01-08
Resolution2.100
CATH Insert Date14 Jan, 2010

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
X 15 Jan, 2010 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3frdX00 17 Jan, 2010 3.40.430.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P0A017 DYR_STAAU Staphylococcus aureus Dihydrofolate reductase