PDB 3fli

PDB Information

PDB3FLI
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of XL335 (WAY-362450), a highly potent, selective, and orally active agonist of the farnesoid X receptor (FXR).
Flatt, B., Martin, R., Wang, T.L., Mahaney, P., Murphy, B., Gu, X.H., Foster, P., Li, J., Pircher, P., Petrowski, M., Schulman, I., Westin, S., Wrobel, J., Yan, G., Bischoff, E., Daige, C., Mohan, R.
J.Med.Chem.
HeaderTranscription
Released2008-12-18
Resolution2.000
CATH Insert Date24 Dec, 2009

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 25 Dec, 2009 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3fliA00 07 Jan, 2010 1.10.565.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q96RI1 NR1H4_HUMAN Homo sapiens Bile acid receptor
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