PDB 3e51

PDB Links
Overview

PDB Information

PDB	3E51
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Hepatitis C virus (isolate BK)
Primary Citation	Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda(6)-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 5: Exploration of pyridazinones containing 6-amino-substituents. Dragovich, P.S., Blazel, J.K., Ellis, D.A., Han, Q., Kamran, R., Kissinger, C.R., LeBrun, L.A., Li, L.S., Murphy, D.E., Noble, M., Patel, R.A., Ruebsam, F., Sergeeva, M.V., Shah, A.M., Showalter, R.E., Tran, C.V., Tsan, M., Webber, S.E., Kirkovsky, L., Zhou, Y. Bioorg.Med.Chem.Lett.
Header	Transferase
Released	2008-08-12
Resolution	1.900
CATH Insert Date	20 Aug, 2009

PDB Images (11)

Image of CATH 3e51

3e51

PDB 3e51

Image of CATH 3e51A

3e51A

PDB Chain 3e51A

Image of CATH 3e51B

3e51B

PDB Chain 3e51B

Image of CATH 3e51A01

3e51A01

CATH Domain 3e51A01

Image of CATH 3e51A02

3e51A02

CATH Domain 3e51A02

Image of CATH 3e51A03

3e51A03

CATH Domain 3e51A03

Image of CATH 3e51A04

3e51A04

CATH Domain 3e51A04

Image of CATH 3e51B01

3e51B01

CATH Domain 3e51B01

Image of CATH 3e51B02

3e51B02

CATH Domain 3e51B02

Image of CATH 3e51B03

3e51B03

CATH Domain 3e51B03

Image of CATH 3e51B04

3e51B04

CATH Domain 3e51B04

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	20 Aug, 2009	Chopped
B	20 Aug, 2009	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3e51A01	03 Oct, 2013		Holding pen
3e51A02	03 Oct, 2013		Holding pen
3e51A03	03 Oct, 2013	3.30.70.270	Assigned
3e51A04	03 Oct, 2013		Holding pen
3e51B01	03 Oct, 2013		Holding pen
3e51B02	03 Oct, 2013		Holding pen
3e51B03	03 Oct, 2013	3.30.70.270	Assigned
3e51B04	03 Oct, 2013		Holding pen

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P26663	POLG_HCVBK	Hepatitis C virus (isolate BK)	Genome polyprotein
P26663	POLG_HCVBK	Hepatitis C virus (isolate BK)	Genome polyprotein