PDB 3ds6

PDB Information

PDB3DS6
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of highly selective and potent p38 inhibitors based on a phthalazine scaffold.
Herberich, B., Cao, G.Q., Chakrabarti, P.P., Falsey, J.R., Pettus, L., Rzasa, R.M., Reed, A.B., Reichelt, A., Sham, K., Thaman, M., Wurz, R.P., Xu, S., Zhang, D., Hsieh, F., Lee, M.R., Syed, R., Li, V., Grosfeld, D., Plant, M.H., Henkle, B., Sherman, L., Middleton, S., Wong, L.M., Tasker, A.S.
J.Med.Chem.
HeaderTransferase
Released2008-07-11
Resolution2.900
CATH Insert Date09 Oct, 2008

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 09 Oct, 2008 Chopped
B 09 Oct, 2008 Chopped
C 09 Oct, 2008 Chopped
D 09 Oct, 2008 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3ds6A01 11 Oct, 2008 3.30.200.20 Assigned
3ds6A02 11 Oct, 2008 1.10.510.10 Assigned
3ds6B01 11 Oct, 2008 3.30.200.20 Assigned
3ds6B02 11 Oct, 2008 1.10.510.10 Assigned
3ds6C01 11 Oct, 2008 3.30.200.20 Assigned
3ds6C02 11 Oct, 2008 1.10.510.10 Assigned
3ds6D01 11 Oct, 2008 3.30.200.20 Assigned
3ds6D02 11 Oct, 2008 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q16539 MK14_HUMAN Homo sapiens Mitogen-activated protein kinase 14
Q16539 MK14_HUMAN Homo sapiens Mitogen-activated protein kinase 14
Q16539 MK14_HUMAN Homo sapiens Mitogen-activated protein kinase 14
Q16539 MK14_HUMAN Homo sapiens Mitogen-activated protein kinase 14