PDB Information

Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Mutated, structurally altered caspase-1 with decreased enzymatic and increased RIP2-meditated inflammatory activity leads to a new type of periodic fever (ICE fever).
Rosen-Wolff, A., Romanowski, M.J., Ritter, L., Flecks, S., Quoos, N., Gramatt, J., Petzold, C., Nguyen, H.D., Gahr, M., Roesler, J.
To be Published
HeaderHydrolase/Hydrolase Inhibitor
CATH Insert Date04 Mar, 2010

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2010 Chopped
B 05 Mar, 2010 Chopped
C 01 Aug, 2011 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3d6hA00 23 Mar, 2010 Assigned
3d6hB00 23 Mar, 2010 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P29466 CASP1_HUMAN Homo sapiens Caspase-1
P29466 CASP1_HUMAN Homo sapiens Caspase-1