PDB 3d5m

PDB Information

PDB3D5M
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus (isolate BK)
Primary Citation
Structure-based design, synthesis, and biological evaluation of 1,1-dioxoisothiazole and benzo[b]thiophene-1,1-dioxide derivatives as novel inhibitors of hepatitis C virus NS5B polymerase.
Kim, S.H., Tran, M.T., Ruebsam, F., Xiang, A.X., Ayida, B., McGuire, H., Ellis, D., Blazel, J., Tran, C.V., Murphy, D.E., Webber, S.E., Zhou, Y., Shah, A.M., Tsan, M., Showalter, R.E., Patel, R., Gobbi, A., LeBrun, L.A., Bartkowski, D.M., Nolan, T.G., Norris, D.A., Sergeeva, M.V., Kirkovsky, L., Zhao, Q., Han, Q., Kissinger, C.R.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2008-05-16
Resolution2.200
CATH Insert Date16 Aug, 2009

PDB Images (11)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped
B 16 Aug, 2009 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3d5mA01 03 Oct, 2013 Holding pen
3d5mA02 03 Oct, 2013 Holding pen
3d5mA03 03 Oct, 2013 3.30.70.270 Assigned
3d5mA04 03 Oct, 2013 Holding pen
3d5mB01 03 Oct, 2013 Holding pen
3d5mB02 03 Oct, 2013 Holding pen
3d5mB03 03 Oct, 2013 3.30.70.270 Assigned
3d5mB04 03 Oct, 2013 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P26663 POLG_HCVBK Hepatitis C virus (isolate BK) Genome polyprotein
P26663 POLG_HCVBK Hepatitis C virus (isolate BK) Genome polyprotein
CATH-Gene3D is a Global Biodata Core Resource Learn more...