PDB 3d28

PDB Information

PDB3D28
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus (isolate BK)
Primary Citation
Structure-based design, synthesis, and biological evaluation of 1,1-dioxoisothiazole and benzo[b]thiophene-1,1-dioxide derivatives as novel inhibitors of hepatitis C virus NS5B polymerase.
Kim, S.H., Tran, M.T., Ruebsam, F., Xiang, A.X., Ayida, B., McGuire, H., Ellis, D., Blazel, J., Tran, C.V., Murphy, D.E., Webber, S.E., Zhou, Y., Shah, A.M., Tsan, M., Showalter, R.E., Patel, R., Gobbi, A., LeBrun, L.A., Bartkowski, D.M., Nolan, T.G., Norris, D.A., Sergeeva, M.V., Kirkovsky, L., Zhao, Q., Han, Q., Kissinger, C.R.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2008-05-07
Resolution2.300
CATH Insert Date16 Aug, 2009

PDB Images (11)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped
B 16 Aug, 2009 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3d28A01 03 Oct, 2013 Holding pen
3d28A02 03 Oct, 2013 Holding pen
3d28A03 03 Oct, 2013 3.30.70.270 Assigned
3d28A04 03 Oct, 2013 Holding pen
3d28B01 14 Jul, 2010 Holding pen
3d28B02 14 Jul, 2010 Holding pen
3d28B03 14 Jul, 2010 3.30.70.270 Assigned
3d28B04 14 Jul, 2010 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P26663 POLG_HCVBK Hepatitis C virus (isolate BK) Genome polyprotein
P26663 POLG_HCVBK Hepatitis C virus (isolate BK) Genome polyprotein