PDB 3byz

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Overview

PDB Information

PDB	3BYZ
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 mice. Johansson, L., Fotsch, C., Bartberger, M.D., Castro, V.M., Chen, M., Emery, M., Gustafsson, S., Hale, C., Hickman, D., Homan, E., Jordan, S.R., Komorowski, R., Li, A., McRae, K., Moniz, G., Matsumoto, G., Orihuela, C., Palm, G., Veniant, M., Wang, M., Williams, M., Zhang, J. J.Med.Chem.
Header	Oxidoreductase
Released	2008-01-16
Resolution	2.690
CATH Insert Date	21 Feb, 2008

PDB Images (9)

Image of CATH 3byz

3byz

PDB 3byz

Image of CATH 3byzA

3byzA

PDB Chain 3byzA

Image of CATH 3byzB

3byzB

PDB Chain 3byzB

Image of CATH 3byzC

3byzC

PDB Chain 3byzC

Image of CATH 3byzD

3byzD

PDB Chain 3byzD

Image of CATH 3byzA00

3byzA00

CATH Domain 3byzA00

Image of CATH 3byzB00

3byzB00

CATH Domain 3byzB00

Image of CATH 3byzC00

3byzC00

CATH Domain 3byzC00

Image of CATH 3byzD00

3byzD00

CATH Domain 3byzD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	21 Feb, 2008	Chopped
B	21 Feb, 2008	Chopped
C	21 Feb, 2008	Chopped
D	21 Feb, 2008	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3byzA00	05 Dec, 2008	3.40.50.720	Assigned
3byzB00	05 Dec, 2008	3.40.50.720	Assigned
3byzC00	05 Dec, 2008	3.40.50.720	Assigned
3byzD00	05 Dec, 2008	3.40.50.720	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1