PDB 3bx5

PDB Information

PDB3BX5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
The discovery of (R)-2-(sec-butylamino)-N-(2-methyl-5-(methylcarbamoyl)phenyl) thiazole-5-carboxamide (BMS-640994)-A potent and efficacious p38alpha MAP kinase inhibitor
Hynes, J., Wu, H., Pitt, S., Shen, D.R., Zhang, R., Schieven, G.L., Gillooly, K.M., Shuster, D.J., Taylor, T.L., Yang, X., McIntyre, K.W., McKinnon, M., Zhang, H., Marathe, P.H., Doweyko, A.M., Kish, K., Kiefer, S.E., Sack, J.S., Newitt, J.A., Barrish, J.C., Dodd, J., Leftheris, K.
Bioorg.Med.Chem.Lett.
HeaderSignaling Protein, Transferase
Released2008-01-11
Resolution2.400
CATH Insert Date17 Apr, 2008

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 17 Apr, 2008 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3bx5A01 18 Apr, 2008 3.30.200.20 Assigned
3bx5A02 18 Apr, 2008 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q16539 MK14_HUMAN Homo sapiens Mitogen-activated protein kinase 14