PDB Information

PDB3BSA
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus (isolate BK)
Primary Citation
Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 1: exploration of 7'-substitution of benzothiadiazine.
Zhou, Y., Webber, S.E., Murphy, D.E., Li, L.S., Dragovich, P.S., Tran, C.V., Sun, Z., Ruebsam, F., Shah, A.M., Tsan, M., Showalter, R.E., Patel, R., Li, B., Zhao, Q., Han, Q., Hermann, T., Kissinger, C.R., Lebrun, L., Sergeeva, M.V., Kirkovsky, L.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2007-12-23
Resolution2.300
CATH Insert Date25 Dec, 2008

PDB Images (11)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 25 Dec, 2008 Chopped
B 25 Dec, 2008 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3bsaA01 03 Oct, 2013 Holding pen
3bsaA02 03 Oct, 2013 Holding pen
3bsaA03 03 Oct, 2013 3.30.70.270 Assigned
3bsaA04 03 Oct, 2013 Holding pen
3bsaB01 03 Oct, 2013 Holding pen
3bsaB02 03 Oct, 2013 Holding pen
3bsaB03 03 Oct, 2013 3.30.70.270 Assigned
3bsaB04 03 Oct, 2013 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P26663 POLG_HCVBK Hepatitis C virus (isolate BK) Genome polyprotein
P26663 POLG_HCVBK Hepatitis C virus (isolate BK) Genome polyprotein