PDB 3br9

PDB Information

PDB3BR9
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus
Primary Citation
Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 1: exploration of 7'-substitution of benzothiadiazine.
Zhou, Y., Webber, S.E., Murphy, D.E., Li, L.S., Dragovich, P.S., Tran, C.V., Sun, Z., Ruebsam, F., Shah, A.M., Tsan, M., Showalter, R.E., Patel, R., Li, B., Zhao, Q., Han, Q., Hermann, T., Kissinger, C.R., Lebrun, L., Sergeeva, M.V., Kirkovsky, L.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2007-12-21
Resolution2.300
CATH Insert Date25 Dec, 2008

PDB Images (11)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 25 Dec, 2008 Chopped
B 25 Dec, 2008 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3br9A01 03 Oct, 2013 Holding pen
3br9A02 03 Oct, 2013 Holding pen
3br9A03 03 Oct, 2013 3.30.70.270 Assigned
3br9A04 03 Oct, 2013 Holding pen
3br9B01 03 Oct, 2013 Holding pen
3br9B02 03 Oct, 2013 Holding pen
3br9B03 03 Oct, 2013 3.30.70.270 Assigned
3br9B04 03 Oct, 2013 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P26663 POLG_HCVBK Hepatitis C virus (isolate BK) Genome polyprotein
P26663 POLG_HCVBK Hepatitis C virus (isolate BK) Genome polyprotein