PDB 3arn
PDB Information
| PDB | 3ARN |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Discovery of a novel class of potent human deoxyuridine triphosphatase inhibitors remarkably enhancing the antitumor activity of thymidylate synthase inhibitors
J.Med.Chem.
|
| Header | Hydrolase/Hydrolase Inhibitor |
| Released | 2010-12-03 |
| Resolution | 1.800 |
| CATH Insert Date | 23 Jan, 2011 |
PDB Images (7)
PDB Prints
PDB Chains (3)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 24 Jan, 2011 | Chopped |
| B | 24 Jan, 2011 | Chopped |
| C | 24 Jan, 2011 | Chopped |
CATH Domains (3)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 3arnA00 | 12 Jul, 2011 | 2.70.40.10 | Assigned |
| 3arnB00 | 12 Jul, 2011 | 2.70.40.10 | Assigned |
| 3arnC00 | 12 Jul, 2011 | 2.70.40.10 | Assigned |
UniProtKB Entries (3)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P33316 | DUT_HUMAN | Homo sapiens | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial |
| P33316 | DUT_HUMAN | Homo sapiens | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial |
| P33316 | DUT_HUMAN | Homo sapiens | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial |
