PDB 2za5

PDB Information

PDB2ZA5
MethodX-RAY DIFFRACTION
Host OrganismPichia pastoris
Gene SourceHomo sapiens
Primary Citation
Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives
Costanzo, M.J., Yabut, S.C., Zhang, H.-C., White, K.B., de Garavilla, L., Wang, Y., Minor, L.K., Tounge, B.A., Barnakov, A.N., Lewandowski, F., Milligan, C., Spurlino, J.C., Abraham, W.M., Boswell-Smith, V., Page, C.P., Maryanoff, B.E.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2007-10-02
Resolution2.300
CATH Insert Date28 Feb, 2008

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 Feb, 2008 Chopped
B 28 Feb, 2008 Chopped
C 28 Feb, 2008 Chopped
D 28 Feb, 2008 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2za5A01 29 Feb, 2008 2.40.10.10 Assigned
2za5A02 29 Feb, 2008 2.40.10.10 Assigned
2za5B01 02 Mar, 2008 2.40.10.10 Assigned
2za5B02 02 Mar, 2008 2.40.10.10 Assigned
2za5C01 02 Mar, 2008 2.40.10.10 Assigned
2za5C02 02 Mar, 2008 2.40.10.10 Assigned
2za5D01 02 Mar, 2008 2.40.10.10 Assigned
2za5D02 02 Mar, 2008 2.40.10.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P20231 TRYB2_HUMAN Homo sapiens Tryptase beta-2
P20231 TRYB2_HUMAN Homo sapiens Tryptase beta-2
P20231 TRYB2_HUMAN Homo sapiens Tryptase beta-2
P20231 TRYB2_HUMAN Homo sapiens Tryptase beta-2
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