PDB Information

PDB2Z4X
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceSaccharomyces cerevisiae
Primary Citation
Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation
Chen, C.K.-M., Hudock, M.P., Zhang, Y., Guo, R.-T., Cao, R., No, J.H., Liang, P.-H., Ko, T.-P., Chang, T.-H., Chang, S.-C., Song, Y., Axelson, J., Kumar, A., Wang, A.H.-J., Oldfield, E.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2007-06-26
Resolution1.900
CATH Insert Date23 Jul, 2008

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 24 Jul, 2008 Chopped
B 24 Jul, 2008 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2z4xA00 18 Mar, 2011 1.10.600.10 Assigned
2z4xB00 18 Mar, 2011 1.10.600.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q12051 GGPPS_YEAST Saccharomyces cerevisiae S288C Geranylgeranyl pyrophosphate synthase
Q12051 GGPPS_YEAST Saccharomyces cerevisiae S288C Geranylgeranyl pyrophosphate synthase