PDB 2yem

PDB Information

PDB2YEM
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Discovery and Characterization of Small Molecule Inhibitors of the Bet Family Bromodomains.
Chung, C.W., Coste, H., White, J.H., Mirguet, O., Wilde, J., Gosmini, R.L., Delves, C., Magny, S.M., Woodward, R., Hughes, S.A., Boursier, E.V., Flynn, H., Bouillot, A.M., Bamborough, P., Brusq, J.M., Gellibert, F.J., Jones, E.J., Riou, A.M., Homes, P., Martin, S.L., Uings, I.J., Toum, J., Clement, C.A., Boullay, A.B., Grimley, R.L., Blandel, F.M., Prinjha, R.K., Lee, K., Kirilovsky, J., Nicodeme, E.
J.Med.Chem.
HeaderSignaling Protein
Released2011-03-25
Resolution2.300
CATH Insert Date19 Jun, 2011

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 20 Jun, 2011 Chopped
B 20 Jun, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2yemA00 23 Jun, 2011 1.20.920.10 Assigned
2yemB00 23 Jun, 2011 1.20.920.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4