PDB 2yek

PDB Information

PDB2YEK
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Discovery and Characterization of Small Molecule Inhibitors of the Bet Family Bromodomains.
Chung, C.W., Coste, H., White, J.H., Mirguet, O., Wilde, J., Gosmini, R.L., Delves, C., Magny, S.M., Woodward, R., Hughes, S.A., Boursier, E.V., Flynn, H., Bouillot, A.M., Bamborough, P., Brusq, J.M., Gellibert, F.J., Jones, E.J., Riou, A.M., Homes, P., Martin, S.L., Uings, I.J., Toum, J., Clement, C.A., Boullay, A.B., Grimley, R.L., Blandel, F.M., Prinjha, R.K., Lee, K., Kirilovsky, J., Nicodeme, E.
J.Med.Chem.
HeaderSignaling Protein
Released2011-03-25
Resolution1.980
CATH Insert Date19 Jun, 2011

PDB Images (7)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 20 Jun, 2011 Chopped
B 20 Jun, 2011 Chopped
C 20 Jun, 2011 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
2yekA00 23 Jun, 2011 1.20.920.10 Assigned
2yekB00 23 Jun, 2011 1.20.920.10 Assigned
2yekC00 23 Jun, 2011 1.20.920.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P25440 BRD2_HUMAN Homo sapiens Bromodomain-containing protein 2
P25440 BRD2_HUMAN Homo sapiens Bromodomain-containing protein 2
P25440 BRD2_HUMAN Homo sapiens Bromodomain-containing protein 2