PDB 2xnn

PDB Information

PDB2XNN
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Benzimidazole Inhibitors Induce a Dfg-Out Conformation of Never in Mitosis Gene A-Related Kinase 2 (Nek2) without Binding to the Back Pocket and Reveal a Nonlinear Structure-Activity Relationship.
Solanki, S., Innocenti, P., Mas-Droux, C., Boxall, K., Barillari, C., Van Montfort, R.L., Aherne, G.W., Bayliss, R., Hoelder, S.
J.Med.Chem.
HeaderTransferase
Released2010-08-05
Resolution2.500
CATH Insert Date03 Apr, 2011

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 04 Apr, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2xnnA01 06 Apr, 2011 3.30.200.20 Assigned
2xnnA02 06 Apr, 2011 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P51955 NEK2_HUMAN Homo sapiens Serine/threonine-protein kinase Nek2