PDB 2xbv

PDB Information

PDB2XBV
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Discovery of a Factor Xa Inhibitor (3R,4R)-1-(2,2-Difluoro-Ethyl)-Pyrrolidine-3,4-Dicarboxylic Acid 3-[(5-Chloro-Pyridin-2-Yl)-Amide] 4-{[2-Fluoro-4-(2-Oxo-2H-Pyridin-1-Yl)-Phenyl]-Amide} as a Clinical Candidate.
Anselm, L., Banner, D.W., Benz, J., Groebke Zbinden, K., Himber, J., Hilpert, H., Huber, W., Kuhn, B., Mary, J.L., Otteneder, M.B., Panday, N., Ricklin, F., Stahl, M., Thomi, S., Haap, W.
Bioorg.Med.Chem.
HeaderBlood Clotting
Released2010-04-15
Resolution1.660
CATH Insert Date15 Aug, 2010

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2010 Chopped
L 16 Aug, 2010 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
2xbvA01 24 Aug, 2010 2.40.10.10 Assigned
2xbvA02 24 Aug, 2010 2.40.10.10 Assigned
2xbvL00 24 Aug, 2010 2.10.25.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00742 FA10_HUMAN Homo sapiens Coagulation factor X
P00742 FA10_HUMAN Homo sapiens Coagulation factor X