PDB 2wpf

PDB Information

PDB2WPF
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceTRYPANOSOMA BRUCEI
Primary Citation
Dihydroquinazolines as a Novel Class of Trypanosoma Brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of Their Binding Mode by Protein Crystallography.
Patterson, S., Alphey, M.S., Jones, D.C., Shanks, E.J., Street, I.P., Frearson, J.A., Wyatt, P.G., Gilbert, I.H., Fairlamb, A.H.
J.Med.Chem.
HeaderOxidoreductase
Released2009-08-06
Resolution1.900
CATH Insert Date17 Oct, 2010

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 18 Oct, 2010 Chopped
B 18 Oct, 2010 Chopped
C 18 Oct, 2010 Chopped
D 18 Oct, 2010 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
2wpfA01 17 Feb, 2011 3.50.50.60 Assigned
2wpfA02 17 Feb, 2011 3.50.50.60 Assigned
2wpfA03 17 Feb, 2011 3.30.390.30 Assigned
2wpfB01 17 Feb, 2011 3.50.50.60 Assigned
2wpfB02 17 Feb, 2011 3.50.50.60 Assigned
2wpfB03 17 Feb, 2011 3.30.390.30 Assigned
2wpfC01 17 Feb, 2011 3.50.50.60 Assigned
2wpfC02 17 Feb, 2011 3.50.50.60 Assigned
2wpfC03 17 Feb, 2011 3.30.390.30 Assigned
2wpfD01 17 Feb, 2011 3.50.50.60 Assigned
2wpfD02 17 Feb, 2011 3.50.50.60 Assigned
2wpfD03 17 Feb, 2011 3.30.390.30 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase