PDB 2wp5

PDB Information

PDB2WP5
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceTRYPANOSOMA BRUCEI
Primary Citation
Dihydroquinazolines as a Novel Class of Trypanosoma Brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of Their Binding Mode by Protein Crystallography.
Patterson, S., Alphey, M.S., Jones, D.C., Shanks, E.J., Street, I.P., Frearson, J.A., Wyatt, P.G., Gilbert, I.H., Fairlamb, A.H.
J.Med.Chem.
HeaderOxidoreductase
Released2009-08-03
Resolution2.800
CATH Insert Date17 Oct, 2010

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 18 Oct, 2010 Chopped
B 18 Oct, 2010 Chopped
C 18 Oct, 2010 Chopped
D 18 Oct, 2010 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
2wp5A01 17 Feb, 2011 3.50.50.60 Assigned
2wp5A02 17 Feb, 2011 3.50.50.60 Assigned
2wp5A03 17 Feb, 2011 3.30.390.30 Assigned
2wp5B01 17 Feb, 2011 3.50.50.60 Assigned
2wp5B02 17 Feb, 2011 3.50.50.60 Assigned
2wp5B03 17 Feb, 2011 3.30.390.30 Assigned
2wp5C01 17 Feb, 2011 3.50.50.60 Assigned
2wp5C02 17 Feb, 2011 3.50.50.60 Assigned
2wp5C03 17 Feb, 2011 3.30.390.30 Assigned
2wp5D01 17 Feb, 2011 3.50.50.60 Assigned
2wp5D02 17 Feb, 2011 3.50.50.60 Assigned
2wp5D03 17 Feb, 2011 3.30.390.30 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase