PDB 2wow

PDB Information

PDB2WOW
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceTRYPANOSOMA BRUCEI
Primary Citation
Dihydroquinazolines as a Novel Class of Trypanosoma Brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of Their Binding Mode by Protein Crystallography.
Patterson, S., Alphey, M.S., Jones, D.C., Shanks, E.J., Street, I.P., Frearson, J.A., Wyatt, P.G., Gilbert, I.H., Fairlamb, A.H.
J.Med.Chem.
HeaderOxidoreductase
Released2009-07-30
Resolution2.200
CATH Insert Date15 Aug, 2010

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2010 Chopped
B 16 Aug, 2010 Chopped
C 16 Aug, 2010 Chopped
D 16 Aug, 2010 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
2wowA01 19 Aug, 2010 3.50.50.60 Assigned
2wowA02 19 Aug, 2010 3.50.50.60 Assigned
2wowA03 19 Aug, 2010 3.30.390.30 Assigned
2wowB01 19 Aug, 2010 3.50.50.60 Assigned
2wowB02 19 Aug, 2010 3.50.50.60 Assigned
2wowB03 19 Aug, 2010 3.30.390.30 Assigned
2wowC01 19 Aug, 2010 3.50.50.60 Assigned
2wowC02 19 Aug, 2010 3.50.50.60 Assigned
2wowC03 19 Aug, 2010 3.30.390.30 Assigned
2wowD01 19 Aug, 2010 3.50.50.60 Assigned
2wowD02 19 Aug, 2010 3.50.50.60 Assigned
2wowD03 19 Aug, 2010 3.30.390.30 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase