PDB 2wov

PDB Information

PDB2WOV
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceTRYPANOSOMA BRUCEI
Primary Citation
Dihydroquinazolines as a Novel Class of Trypanosoma Brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of Their Binding Mode by Protein Crystallography.
Patterson, S., Alphey, M.S., Jones, D.C., Shanks, E.J., Street, I.P., Frearson, J.A., Wyatt, P.G., Gilbert, I.H., Fairlamb, A.H.
J.Med.Chem.
HeaderOxidoreductase
Released2009-07-30
Resolution2.500
CATH Insert Date15 Aug, 2010

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2010 Chopped
B 16 Aug, 2010 Chopped
C 16 Aug, 2010 Chopped
D 16 Aug, 2010 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
2wovA01 19 Aug, 2010 3.50.50.60 Assigned
2wovA02 19 Aug, 2010 3.50.50.60 Assigned
2wovA03 19 Aug, 2010 3.30.390.30 Assigned
2wovB01 19 Aug, 2010 3.50.50.60 Assigned
2wovB02 19 Aug, 2010 3.50.50.60 Assigned
2wovB03 19 Aug, 2010 3.30.390.30 Assigned
2wovC01 19 Aug, 2010 3.50.50.60 Assigned
2wovC02 19 Aug, 2010 3.50.50.60 Assigned
2wovC03 19 Aug, 2010 3.30.390.30 Assigned
2wovD01 19 Aug, 2010 3.50.50.60 Assigned
2wovD02 19 Aug, 2010 3.50.50.60 Assigned
2wovD03 19 Aug, 2010 3.30.390.30 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase