PDB 2woi

PDB Information

PDB2WOI
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceTRYPANOSOMA BRUCEI
Primary Citation
Dihydroquinazolines as a Novel Class of Trypanosoma Brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of Their Binding Mode by Protein Crystallography.
Patterson, S., Alphey, M.S., Jones, D.C., Shanks, E.J., Street, I.P., Frearson, J.A., Wyatt, P.G., Gilbert, I.H., Fairlamb, A.H.
J.Med.Chem.
HeaderOxidoreductase
Released2009-07-24
Resolution2.100
CATH Insert Date15 Aug, 2010

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2010 Chopped
B 16 Aug, 2010 Chopped
C 16 Aug, 2010 Chopped
D 16 Aug, 2010 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
2woiA01 19 Aug, 2010 3.50.50.60 Assigned
2woiA02 19 Aug, 2010 3.50.50.60 Assigned
2woiA03 19 Aug, 2010 3.30.390.30 Assigned
2woiB01 19 Aug, 2010 3.50.50.60 Assigned
2woiB02 19 Aug, 2010 3.50.50.60 Assigned
2woiB03 19 Aug, 2010 3.30.390.30 Assigned
2woiC01 19 Aug, 2010 3.50.50.60 Assigned
2woiC02 19 Aug, 2010 3.50.50.60 Assigned
2woiC03 19 Aug, 2010 3.30.390.30 Assigned
2woiD01 19 Aug, 2010 3.50.50.60 Assigned
2woiD02 19 Aug, 2010 3.50.50.60 Assigned
2woiD03 19 Aug, 2010 3.30.390.30 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase